To view this video please enable JavaScript, and consider upgrading to a web browser that supports HTML5 video Movie 2 Sciatic nerve injury model (Cont) Developmental downregulation of LIS1 expression limits axonal extension and allows axon pruning Kanako Kumamoto, Tokuichi Iguchi, Ryuichi Ishida, Takuya Uemura, Makoto Sato, and Shinji Hirotsune Biology Open 2017. 6:1041-1055; doi: 10.1242/bio.025999 Download Original Video