OptoEphB2 activation induce filopodial protrusions in the dendrite. OptoEphB2 was locally photo-activated in the dendrite of cultured hippocampal neurons. The cell co-expressed OptoEphB2 and mCherry. Fluorescence signal is from mCherry. The blue circle denotes the area of blue light illumination. The blue dot denotes the time of blue light illumination.