Movie 1

Filament formation by eIF2B induced by energy depletion. Live-cell time-lapse microscopy of Gcn3-sfGFP(V206R) cells grown to log phase in SC medium containing 2% glucose. The cells were then depleted of energy as described in material and methods. The movie starts at the time point of energy depletion.

Filament formation by the translation factor eIF2B regulates protein synthesis in starved cells

Elisabeth Nüske, Guendalina Marini, Doris Richter, Weihua Leng, Aliona Bogdanova, Titus M. Franzmann, Gaia Pigino, and Simon Alberti

Biology Open 2020. 9:None-None; doi: 10.1242/bio.046391