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Movie 3

Emergence of canonical Wnt signaling in mESC-derived optic vesicle-like structure
Canonical Wnt signaling was activated autonomously at the proximal region on the one side of optic vesicle-like structure. 7tcf::mCherry (red), Rx::GFP (green).

Emergence of dorsal-ventral polarity in ESC-derived retinal tissue

Yuiko Hasegawa, Nozomu Takata, Satoru Okuda, Masako Kawada, Mototsugu Eiraku, and Yoshiki Sasai

Development 2016. 143:3895-3906; doi: 10.1242/dev.134601