Movie 4

Involvement of canonical Wnt signaling dynamics with formation of D-V morphological characteristics in mESC-derived optic vesicle-like structure.
The NR on the side with the stronger Wnt activation invaginated faster than on the opposite side. 7tcf::tdTomato (red).

Emergence of dorsal-ventral polarity in ESC-derived retinal tissue

Yuiko Hasegawa, Nozomu Takata, Satoru Okuda, Masako Kawada, Mototsugu Eiraku, and Yoshiki Sasai

Development 2016. 143:3895-3906; doi: 10.1242/dev.134601