Movie 5

Induction of canonical Wnt signaling by local application in vitro
In Rx+ neuroepithelium, 7tcf::tdTomato expression was specifically induced in the proximity of local gradient of CHIR. Alexa-647 (blue), 7tcf::tdTomato (red), Rx::GFP (green).

Emergence of dorsal-ventral polarity in ESC-derived retinal tissue

Yuiko Hasegawa, Nozomu Takata, Satoru Okuda, Masako Kawada, Mototsugu Eiraku, and Yoshiki Sasai

Development 2016. 143:3895-3906; doi: 10.1242/dev.134601