To view this video please enable JavaScript, and consider upgrading to a web browser that supports HTML5 video Movie 5 Induction of canonical Wnt signaling by local application in vitroIn Rx+ neuroepithelium, 7tcf::tdTomato expression was specifically induced in the proximity of local gradient of CHIR. Alexa-647 (blue), 7tcf::tdTomato (red), Rx::GFP (green). Emergence of dorsal-ventral polarity in ESC-derived retinal tissue Yuiko Hasegawa, Nozomu Takata, Satoru Okuda, Masako Kawada, Mototsugu Eiraku, and Yoshiki Sasai Development 2016. 143:3895-3906; doi: 10.1242/dev.134601 Download Original Video