Movie 4

Prdm16-GOF cells show characteristic irregular migration in VZ, MAZ, and IZ. IUE of control (left) or CAG-Prdm (right) was performed at E14.5. Cortical slices were prepared after 42 h and cultured under observation with a FV1000 confocal laser microscope. Time-lapse imaging data were then acquired automatically every 15 min for 28 h.

Prdm16 is crucial for progression of the multipolar phase during neural differentiation of the developing neocortex

Mayuko Inoue, Ryota Iwai, Hidenori Tabata, Daijiro Konno, Mariko Komabayashi-Suzuki, Chisato Watanabe, Hiroko Iwanari, Yasuhiro Mochizuki, Takao Hamakubo, Fumio Matsuzaki, Koh-ichi Nagata, and Ken-ichi Mizutani

Development 2017. 144:385-399; doi: 10.1242/dev.136382