Movie 1
Serial block-face scanning electron microscopy shows a blood vessel coated with collagen I and associated with osteoblast. 3D reconstruction using 321 images generated by SBF-SEM analysis of humerus from an E16.5 mouse embryo. A blood vessel consisting of three ECs and carrying a red blood cell (different shades of red) is covered with collagen (green) and associated with osteoblast (blue).
Deposition of collagen type I onto skeletal endothelium reveals a new role for blood vessels in regulating bone morphology
Development 2016. 143:3933-3943; doi: 10.1242/dev.139253