Movie 10

Single and combined effects of Ca2+ transients (pulse) and constrictive nature of apical cell surface (Acn) on the modeled epithelial tissue. Cells outlined in bold are in an active state. The simulation time is shown at the top left; simulation conditions are indicated below each tissue. Frames were captured every 20 simulation times. Movie frame rate: 20 frames/sec.

Distinct intracellular Ca2+ dynamics regulate apical constriction and differentially contribute to neural tube closure

Makoto Suzuki, Masanao Sato, Hiroshi Koyama, Yusuke Hara, Kentaro Hayashi, Naoko Yasue, Hiromi Imamura, Toshihiko Fujimori, Takeharu Nagai, Robert E. Campbell, and Naoto Ueno

Development 2017. 144:1307-1316; doi: 10.1242/dev.141952