Movie 9

woc-mutant EC clones display remnant protrusive activity.
A 120-minute time-lapse movie of MARCM labelled single woc-mutant EC in a wild type germarium. The cell is located in region 2A, a region where ECs usually form elaborate ‘baskets’. woc-mutant ECs, which are surrounded by WT cells, do generate extensions while trying to encapsulate adjacent germ cells (close-bye cysts are outlined). However, these extensions are still shorter and less stable than WT extension. Arrowheads mark a short association of the EC with a single cell of the germline cyst. The presented maximum projection includes 20 z-planes per time point at focal planes 1 μm apart, captured in 2-minute intervals. Scale bar is 10 μm.

Escort cells generate a dynamic compartment for germline stem cell differentiation via combined Stat and Erk signalling

Torsten U. Banisch, Iris Maimon, Tali Dadosh, and Lilach Gilboa

Development 2017. 144:1937-1947; doi: 10.1242/dev.143727