Movie 2

Endogenous mesoderm cell internalization.
Confocal image series of endogenous ppl progenitor cells (green) internalizing at the dorsal germ ring margin in a Tg(-4gsc:eGFP-Hsa.HRAS) embryo injected with LynTagBFP mRNA to label the membrane of all cells (red) and fluorescent Dextran (blue) to label the interstitial fluid. Frame rate, ~ 2 fps; ~ 2.5 min/frame. Scale bar, 20 μm.

Interstitial fluid osmolarity modulates the action of differential tissue surface tension in progenitor cell segregation during gastrulation

S. F. Gabriel Krens, Jim H. Veldhuis, Vanessa Barone, Daniel Čapek, Jean-Léon Maître, G. Wayne Brodland, and Carl-Philipp Heisenberg

Development 2017. 144:1798-1806; doi: 10.1242/dev.144964