Movie 9

Cell protrusion formation of DN-Rac expressing mesoderm cells.
Image series of induced ppl progenitor cell aggregates isolated from a Tg(bAct:utro-mCherry) embryo and seeded on a fibronectin-coated substrate for 1.5 h. Upper panels display bright-field images and lower panels show fluorescent Utrophin-mCherry to label actin. Left panels are WT ppl cells and right panels are DN-Rac expressing ppl cells. Frame rate, ~ 6 fps; 2 min/frame. Scale bar, 10 μm.

Interstitial fluid osmolarity modulates the action of differential tissue surface tension in progenitor cell segregation during gastrulation

S. F. Gabriel Krens, Jim H. Veldhuis, Vanessa Barone, Daniel Čapek, Jean-Léon Maître, G. Wayne Brodland, and Carl-Philipp Heisenberg

Development 2017. 144:1798-1806; doi: 10.1242/dev.144964