To view this video please enable JavaScript, and consider upgrading to a web browser that supports HTML5 video Movie 5 Time-lapse movie of peripheral regions of a Btbd7 KO E13.5 SMG demonstrating loss of dynamic nuclear separation (green and gray) adjacent to unstable clefts (collagen IV, red). Each frame represents a 10 minute time interval. Scale bar, 10 μm. Btbd7 is essential for region-specific epithelial cell dynamics and branching morphogenesis in vivo William P. Daley, Kazue Matsumoto, Andrew D. Doyle, Shaohe Wang, Brian J. DuChez, Kenn Holmbeck, and Kenneth M. Yamada Development 2017. 144:2200-2211; doi: 10.1242/dev.146894 Download Original Video