Movie S2
Chorionioallantoic branching morphogenesis of E8.5 Egfl7-/- conceptuses. Three-dimensional reconstruction of z-stack confocal images of 100μm thick vibratome sections of E8.5 Egfl7-/- conceptuses immunostained for CD31 (green), CYTOKERATIN (red) and nuclear DAPI (blue), showing reduced percentage of chorioallantoic attachment. Scale bar = 200μm.
Altered feto-placental vascularization, feto-placental malperfusion and fetal growth restriction in mice with Egfl7 loss of function
Development 2017. 144:2469-2479; doi: 10.1242/dev.147025