Movie S2

Chorionioallantoic branching morphogenesis of E8.5 Egfl7-/- conceptuses. Three-dimensional reconstruction of z-stack confocal images of 100μm thick vibratome sections of E8.5 Egfl7-/- conceptuses immunostained for CD31 (green), CYTOKERATIN (red) and nuclear DAPI (blue), showing reduced percentage of chorioallantoic attachment. Scale bar = 200μm.

Altered feto-placental vascularization, feto-placental malperfusion and fetal growth restriction in mice with Egfl7 loss of function

Lauretta A. Lacko, Romulo Hurtado, Samantha Hinds, Michael G. Poulos, Jason M. Butler, and Heidi Stuhlmann

Development 2017. 144:2469-2479; doi: 10.1242/dev.147025