Movie S4

Chorionic invaginations of E9.5 Egfl7-/- placentas. Three-dimensional reconstruction of z-stack confocal images of 100μm thick vibratome sections of E9.5 Egfl7-/- conceptuses immunostained for CD31 (green), CYTOKERATIN (red) and nuclear DAPI (blue), showing reduced number of chorionic invaginations. Scale bar = 200μm.

Altered feto-placental vascularization, feto-placental malperfusion and fetal growth restriction in mice with Egfl7 loss of function

Lauretta A. Lacko, Romulo Hurtado, Samantha Hinds, Michael G. Poulos, Jason M. Butler, and Heidi Stuhlmann

Development 2017. 144:2469-2479; doi: 10.1242/dev.147025