Movie 2
premigratory vs migratory PDGF-A chemotaxis
Premigratory (premig.) NC explants do not chemotax towards PDGF-A protein beads compared to their migratory (mig.) counterpart. Both premigratory and migratory NC explants chemotax towards SDF-1 protein coated bead. Scale bar 25 μM (5min frame-1).
PDGF controls contact inhibition of locomotion by regulating N-cadherin during neural crest migration
Development 2017. 144:2456-2468; doi: 10.1242/dev.147926