Movie 3
PDGF-A/PDGFRa dispersion assay
PDGF-A MO and PDGFRa MO explants have decreased dispersion compared to control NC cluster. Addition of PDGF-AA protein can rescue PDGF-A MO, but PDGFRa MO dispersion, scale bar 150μM (25min frame-1).
PDGF controls contact inhibition of locomotion by regulating N-cadherin during neural crest migration
Development 2017. 144:2456-2468; doi: 10.1242/dev.147926