Supplementary Movie S3

Dermal lymphatic vessel contraction is lacking in the absence of SMCs coverage of collecting vessels - overview of PdgfbiLECKO. A PdgfbiLECKO mouse was anaesthetized and the ear was subcutaneously injected with Tritc Dextran, followed by timelapse imaging utilizing a Leica M205FA microscope with a PLANAPO 1.0x objective. Contraction was not observed on the lymphatic vessels. Scale bar, 500 μm.

Smooth muscle cell recruitment to lymphatic vessels requires PDGFB and impacts vessel size but not identity

Yixin Wang, Yi Jin, Maarja Andaloussi Mäe, Yang Zhang, Henrik Ortsäter, Christer Betsholtz, Taija Mäkinen, and Lars Jakobsson

Development 2017. 144:3590-3601; doi: 10.1242/dev.147967