Dermal lymphatic vessel contraction is lacking in the absence of SMCs coverage of collecting vessels - overview of PdgfbiLECKO. A PdgfbiLECKO mouse was anaesthetized and the ear was subcutaneously injected with Tritc Dextran, followed by timelapse imaging utilizing a Leica M205FA microscope with a PLANAPO 1.0x objective. Contraction was not observed on the lymphatic vessels. Scale bar, 500 μm.
Yixin Wang, Yi Jin, Maarja Andaloussi Mäe, Yang Zhang, Henrik Ortsäter, Christer Betsholtz, Taija Mäkinen, and Lars Jakobsson
Development
2017. 144:3590-3601; doi: 10.1242/dev.147967