Movie 2

Roll-over assay with Wg overexpression
Individual wandering 3rd instar wg-Gal4/+ (left) and wg-Gal4>UAS-Wg (right) on a 1% agarose-coated 100x15mm plate. Larvae rolled over using a fine paintbrush to place the ventral midline exactly upwards (t=0). A stopwatch was used to record righting time, until dorsal midline was exactly upwards (time in the bottom right corner of the video).

Notum coordinates synapse development via extracellular regulation of Wingless trans-synaptic signaling

Danielle L. Kopke, Sofia C. Lima, Cyrille Alexandre, and Kendal Broadie

Development 2017. 144:3499-3510; doi: 10.1242/dev.148130