Movie S3

24 hour time-lapse video of endocrine cell migration and deformation in Nrp2 wild type embryonic pancreas explant. Endocrine lineage cells (red) in Nrp2 wild type pancreas (Nrp2+/+; Neurog3-tdTomato) readily display cell migration and cell deformation, such as filopodia extensions. Time-lapse video is created from data in Figure 5.

A radial axis defined by semaphorin-to-neuropilin signaling controls pancreatic islet morphogenesis

Philip T. Pauerstein, Krissie Tellez, Kirk B. Willmarth, Keon Min Park, Brian Hsueh, H. Efsun Arda, Xueying Gu, Haig Aghajanian, Karl Deisseroth, Jonathan A. Epstein, and Seung K. Kim

Development 2017. 144:3744-3754; doi: 10.1242/dev.148684