Movie S4
24 hour time-lapse video of endocrine cell migration and deformation in Nrp2 knockout embryonic pancreas explant. Endocrine lineage cells (red) in Nrp2 knockout pancreas (Nrp2-/-; Neurog3-tdTomato) show limited migration and cell deformation compared to Nrp2 wild type control (Movie S3). Time-lapse video is created from data in Figure 5.
A radial axis defined by semaphorin-to-neuropilin signaling controls pancreatic islet morphogenesis
Development 2017. 144:3744-3754; doi: 10.1242/dev.148684