Movie 1
Reaction-Diffusion model of free BMP4 distribution in differentiating hPSC colonies. The video shows the evolution of free BMP4 distribution in differentiating hPSC colonies in accordance with the BMP4-NOGGIN RD model in a differentiating colony of a 1000μm diameter.
A stepwise model of reaction-diffusion and positional information governs self-organized human peri-gastrulation-like patterning
Development 2017. 144:4298-4312; doi: 10.1242/dev.149658