Movie 1
Epithelial spheres in 3D culture contain beating multiciliated cells. Time-lapse microscopy of spherical colonies derived in 3D Matrigel from sorted Day14 Nkx2-1+ vs. – precursors, reveals beating multiciliated cells. The video was recorded after ≥3 weeks of 3D culture.
Pluripotent stem cell differentiation reveals distinct developmental pathways regulating lung- versus thyroid-lineage specification
Development 2017. 144:3879-3893; doi: 10.1242/dev.150193