Movie 1

DIC time-lapse of a wild-type (left) and a typical noah-1(RNAi) (right) embryo starting at the beginning of elongation. The noah-1(RNAi) embryo starts showing some abnormal signs, a small bulge (arrow) and some extra-embryonic material (arrowhead), at 270 min. Another bulge (arrow at 290 min) and more abundant extra-embryonic material (arrowheads after 270 min) were observed at later time