Movie 3, related to Figure 3.
Evidence of convergence and extension in E14 cochlear explant.
XY (top) and XZ (bottom) views of a 16-hour time-lapse sequence of the mid-apical region of an E14 Atoh1Cre*PR; R26RZsGreen explant (same explant as in Movie 2). Cells become further apart along the extension (X) axis, while converging along the Y-axis. Images were captured at 10 min. intervals.
Cell migration, intercalation and growth regulate mammalian cochlear extension
Development 2017. 144:3766-3776; doi: 10.1242/dev.151761