Movie S1

Microglial activation response to focal laser ablation. Related to Figure 7. Time-lapse recording of microglial response to damage induced by focused laser ablation in brain cortex, observed by in vivo multiphoton imaging. Hoxb8-microglia (yellow) and non-Hoxb8-microglia (green) exhibit very similar behavior in the event of an injury in their surrounding environment.

Two distinct ontogenies confer heterogeneity to mouse brain microglia

Shrutokirti De, Donn Van Deren, Eric Peden, Matt Hockin, Anne Boulet, Simon Titen, and Mario R. Capecchi

Development 2018. 145:None-None; doi: 10.1242/dev.152306