Movie 4

Tagln-Cre:Tgfβr2flx/flx mutant embryos are viable at E14.5. Stereo microscope time lapse of E14.5 Tagln-Cre:Tgfβr2flx/flx embryo freshly collected showing active cardiac output and filled peripheral vascular space.

Transgelin-expressing myofibroblasts orchestrate ventral midline closure through TGFβ signalling

Bashar Aldeiri, Urmas Roostalu, Alessandra Albertini, Jason Wong, Antonino Morabito, and Giulio Cossu

Development 2017. 144:3336-3348; doi: 10.1242/dev.152843