Movie 4

Ex-vivo video-microscopy recording of the Ccdc39prh/prh forebrain medial wall ependymal cilia.
P6 Ccdc39prh/prh ependymal motile cilia in medial wall of the forebrain showing slower beat frequency and a rigid cilia beating patterns (video captured at a rate of 100 frames per second and played back at 5 frames per second) than the wild-type cilia. Scale bar is 10 μm.

A mutation in Ccdc39 causes neonatal hydrocephalus with abnormal motile cilia development in mice

Zakia Abdelhamed, Shawn M. Vuong, Lauren Hill, Crystal Shula, Andrew Timms, David Beier, Kenneth Campbell, Francesco T. Mangano, Rolf W. Stottmann, and June Goto

Development 2018. 145:None-None; doi: 10.1242/dev.154500