Movie 5

Ex-vivo video-microscopy recording of ependymal cilia-generated CSF flow in the central aqueduct of a wild-type mouse.
P7 ependymal motile cilia in the central aqueduct generating vigorous unidirectional CSF fluid flow (video captured at a rate of 10.4 frames per second and played back at 5 frames per second) in wild-type mouse. Scale bar is 10 μm.

A mutation in Ccdc39 causes neonatal hydrocephalus with abnormal motile cilia development in mice

Zakia Abdelhamed, Shawn M. Vuong, Lauren Hill, Crystal Shula, Andrew Timms, David Beier, Kenneth Campbell, Francesco T. Mangano, Rolf W. Stottmann, and June Goto

Development 2018. 145:None-None; doi: 10.1242/dev.154500