Movie S2

Confocal time-lapse video microscopy showing the effects of CK-666 on EGFP-Nrf2-expressing keratinocytes.
CK-666 induces nuclear accumulation of Nrf2. EGFP-Nrf2-expressing keratinocytes were plated on collagen I-coated glass-bottom dishes, imaged prior to and after the addition of CK-666 (100 μM).

Knockout of the Arp2/3 complex in epidermis causes a psoriasis-like disease hallmarked by hyperactivation of transcription factor Nrf2

Rob van der Kammen, Ji-Ying Song, Iris de Rink, Hans Janssen, Stefania Madonna, Claudia Scarponi, Cristina Albanesi, Wim Brugman, and Metello Innocenti

Development 2017. 144:4588-4603; doi: 10.1242/dev.156323