Movie 6
Sif overexpression resembles the aPKC-CAAX phenotype while sif RNAi rescues aPKC-CAAX's phenotype. Sif overexpression resembles the aPKC-CAAX phenotype that displays large ectopic protrusions and outstretched border cells. Expression of sif RNAi rescues aPKC-CAAX's phenotype. Scale bars: 10μm.
aPKC is a key polarity determinant in coordinating the function of three distinct cell polarities during collective migration
Development 2018. 145:None-None; doi: 10.1242/dev.158444