Movie 7

Expression of aPKC-DN fails to rescue the ectopic protrusions phenotype of Sif overexpression. Co-expression of the dominant negative form of aPKC (aPKC-DN) with Sif resulted in the same phenotype of expressing Sif alone. Scale bars: 10μm.

aPKC is a key polarity determinant in coordinating the function of three distinct cell polarities during collective migration

Heng Wang, Zhiqian Qiu, Zehao Xu, Samuel John Chen, Jun Luo, Xiaobo Wang, and Jiong Chen

Development 2018. 145:None-None; doi: 10.1242/dev.158444