To view this video please enable JavaScript, and consider upgrading to a web browser that supports HTML5 video Movie S2 Live imaging of SO+ outgrows showing beating cells. Oct4 regulates the embryonic axis and coordinates exit from pluripotency and germ layer specification in the mouse embryo Carla Mulas, Gloryn Chia, Kenneth Alan Jones, Andrew Christopher Hodgson, Giuliano Giuseppe Stirparo, and Jennifer Nichols Development 2018. 145:None-None; doi: 10.1242/dev.159103 Download Original Video