Movie 6

3D movie of the migrating stream of Robo3-immuoreactive pontine neurons in a Ntn1^-/- E16 embryo. Robo3 pontine neurons fail to reach the midline and a large fraction migrate outside the CNS in to the trigeminal and auditory nerves. Abbreviations: Hind, hindbrain; Mes, mesencephalon; Fr; Fasciculus retroflexus; V, trigeminal nerve; VIII, auditory nerve.