Movie 3

β-catenin null embryonic hearts display reduced right ventricular size and increased percentage of NkxECs. Embryonic hearts from heterozygous (left) and homozygous (right) β-catenin null mutants were serially sectioned and imaged by confocal microscopy. Nuclei (blue), VEGFR2GFP+ ECs (green) and Nkx2.5Cre:tdTomato+ cells (red) are shown.

Wnt inhibition promotes vascular specification of embryonic cardiac progenitors

David E. Reichman, Laura Park, Limor Man, David Redmond, Kenny Chao, Richard P. Harvey, Makoto M. Taketo, Zev Rosenwaks, and Daylon James

Development 2018. 145:None-None; doi: 10.1242/dev.159905