Movie 4

β-catenin gain of function embryos at e11.5 display aberrant cardiac development and reduced NkxECs. β-catenin gain of function mutant embryo was serially sectioned and imaged by confocal microscopy. Nuclei (blue), VEGFR2^GFP+ ECs (green) and Nkx2.5^Cre:tdTomato⁺ cells (red) are shown.

Wnt inhibition promotes vascular specification of embryonic cardiac progenitors

David E. Reichman, Laura Park, Limor Man, David Redmond, Kenny Chao, Richard P. Harvey, Makoto M. Taketo, Zev Rosenwaks, and Daylon James

Development 2018. 145:None-None; doi: 10.1242/dev.159905

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