β-catenin gain of function embryos at e9.0 and e9.5 show reduced vascular density. Embryos from wild type and heterozygous β-catenin gain of function embryos were serially sectioned and imaged by confocal microscopy. Nuclei (blue), VEGFR2GFP+ ECs (green) and Nkx2.5Cre:tdTomato+ cells (red) are shown.
David E. Reichman, Laura Park, Limor Man, David Redmond, Kenny Chao, Richard P. Harvey, Makoto M. Taketo, Zev Rosenwaks, and Daylon James
Development
2018. 145:None-None; doi: 10.1242/dev.159905