Movie 6

β-catenin gain of function embryos at e9.0 and e9.5 show reduced vascular density. Embryos from wild type and heterozygous β-catenin gain of function embryos were serially sectioned and imaged by confocal microscopy. Nuclei (blue), VEGFR2GFP+ ECs (green) and Nkx2.5Cre:tdTomato+ cells (red) are shown.

Wnt inhibition promotes vascular specification of embryonic cardiac progenitors

David E. Reichman, Laura Park, Limor Man, David Redmond, Kenny Chao, Richard P. Harvey, Makoto M. Taketo, Zev Rosenwaks, and Daylon James

Development 2018. 145:None-None; doi: 10.1242/dev.159905