Movie 19

WT:WT sprout
Simulation movie showing a 1:1 WT:WT sprout in which both the green and red cells depict WT cells. The green and red cells are equally competent to occupy the tip position. The green layer underneath the vessel shows the VEGF gradient, which linearly increases towards the tip.

Defective endothelial cell migration in the absence of Cdc42 leads to capillary-venous malformations

Bàrbara Laviña, Marco Castro, Colin Niaudet, Bert Cruys, Alberto Álvarez-Aznar, Peter Carmeliet, Katie Bentley, Cord Brakebusch, Christer Betsholtz, and Konstantin Gaengel

Development 2018. 145:None-None; doi: 10.1242/dev.161182