Movie 9

PDGF signaling promotes sub-marginal protrusion formation in LEM aggregates. The time lapse recording shows mesoderm aggregate on FN-PDGF substratum, where cells underlap each other with large, smooth lamellipodia and can form shingle arrangements.

PDGF-A suppresses contact inhibition during directional collective cell migration

Martina Nagel, and Rudolf Winklbauer

Development 2018. 145:None-None; doi: 10.1242/dev.162651