To view this video please enable JavaScript, and consider upgrading to a web browser that supports HTML5 video Movie 9 PDGF signaling promotes sub-marginal protrusion formation in LEM aggregates. The time lapse recording shows mesoderm aggregate on FN-PDGF substratum, where cells underlap each other with large, smooth lamellipodia and can form shingle arrangements. PDGF-A suppresses contact inhibition during directional collective cell migration Martina Nagel, and Rudolf Winklbauer Development 2018. 145:None-None; doi: 10.1242/dev.162651 Download Original Video