Movie 2

Polarized actin-rich protrusions of migrating endodermal cells in control and gpc4 mutant embryos.
Confocal time-lapse experiments were performed on Tg(sox17:GFP-UTRN) control or gpc4 mutant embryos at TB, using a Ziess LSM700 confocal microscope with a LD C-Apo 40×/NA 1.1 water objective. Images were acquired at 10-sec intervals and movie plays at 5 frames/sec.

Glypican 4 and Mmp14 interact in regulating the migration of anterior endodermal cells by limiting extracellular matrix deposition

Bo Hu, Yuanyuan Gao, Lauren Davies, Stephanie Woo, Jacek Topczewski, Jason R. Jessen, and Fang Lin

Development 2018. 145:None-None; doi: 10.1242/dev.163303