Movie 4

C&E of gpc4-deficient donor cells in wild-type host embryo.
Representative time-lapse movie of anterior endoderm of a Tg(sox17:EGFP) embryo transplanted with sox32-expressing, rhodamine-labeled gpc4-deficient cells (magenta), from 2-5s. Images were captured at 5-min intervals using an epifluorescence microscope (DMI 6000, Leica) with a 5x/NA 0.15 objective. The movie plays at 5 frames/sec.

Glypican 4 and Mmp14 interact in regulating the migration of anterior endodermal cells by limiting extracellular matrix deposition

Bo Hu, Yuanyuan Gao, Lauren Davies, Stephanie Woo, Jacek Topczewski, Jason R. Jessen, and Fang Lin

Development 2018. 145:None-None; doi: 10.1242/dev.163303