Movie 6

Mmp14a/b is required for efficient endoderm C&E during early segmentation.
Time-lapse experiments were performed on control or mmp14a/b MO-injected Tg(sox17:EGFP) embryos from 1-6s, using an epifluorescence microscope (DMI 6000, Leica) with a 5x/NA 0.15 objective. Images were acquired at 5-min intervals. The movie plays at 5 frames/sec.