Movie 6

Mmp14a/b is required for efficient endoderm C&E during early segmentation.
Time-lapse experiments were performed on control or mmp14a/b MO-injected Tg(sox17:EGFP) embryos from 1-6s, using an epifluorescence microscope (DMI 6000, Leica) with a 5x/NA 0.15 objective. Images were acquired at 5-min intervals. The movie plays at 5 frames/sec.

Glypican 4 and Mmp14 interact in regulating the migration of anterior endodermal cells by limiting extracellular matrix deposition

Bo Hu, Yuanyuan Gao, Lauren Davies, Stephanie Woo, Jacek Topczewski, Jason R. Jessen, and Fang Lin

Development 2018. 145:None-None; doi: 10.1242/dev.163303