Rostral extension of the dorsal pancreas anlage in a Hes1−/− midgut explant. Live-imaging of the GFP expressing dorsal pancreatic cells during culture of the explanted midgut from an E9.5 Hes1−/−Pdx1-GFP embryo. Note the lack of dorsal expansion and a rostral extension of the GFP+ cells. Anterior is to the left and dorsal is up.
Mette C. Jørgensen, Kristian H. de Lichtenberg, Caitlin A. Collin, Rasmus Klinck, Jeppe H. Ekberg, Maja S. Engelstoft, Heiko Lickert, and Palle Serup
Development
2018. 145:None-None; doi: 10.1242/dev.163568