Movie 11
Timelapse of prospective nasal optic fissure cell behaviors during wild type optic cup morphogenesis (12-24 hpf). Marked cells exit the midline region, move through the prospective optic stalk domain, and into the ventronasal optic cup and nasal margin of the optic fissure. Cells maintain an elongated morphology throughout the process. Maximum intensity projection of photoconverted Kaede (grayscale) to visualize entire cell morphologies. Time interval between z-stacks, 2.75 minutes. Dorsal view.
Hedgehog signaling regulates cell motility and optic fissure and stalk formation during vertebrate eye morphogenesis
Development 2018. 145:None-None; doi: 10.1242/dev.165068