Movie 18

Timelapse of wild type donor cells in a ptch2tc294z mutant host. Donor cells (magenta) originating in the midline region contribute in a large group to the central retina, or lose bipolar morphology and contribute to the optic stalk. Maximum intensity projection of donor cells (magenta, fluorescent dextran lineage tracer) superimposed on average projection of host membrane label (green, Tg(bactin2:EGFPCAAX)). Time interval between stacks, 7.35 minutes. Dorsal view.

Hedgehog signaling regulates cell motility and optic fissure and stalk formation during vertebrate eye morphogenesis

Hannah B. Gordon, Sarah Lusk, Keith R. Carney, Emily O. Wirick, Brooke Froelich Murray, and Kristen M. Kwan

Development 2018. 145:None-None; doi: 10.1242/dev.165068