Movie 3

Timelapse of ptch2tc294z mutant optic cup morphogenesis. Single confocal section from a 4D data set showing right optic vesicle, ~12-24 hpf. Time interval between z-stacks, 2.75 minutes. Dorsal view. Embryo labeled with EGFP-CAAX (membranes, green) and H2A.F/Z-mCherry (nuclei, magenta).

Hedgehog signaling regulates cell motility and optic fissure and stalk formation during vertebrate eye morphogenesis

Hannah B. Gordon, Sarah Lusk, Keith R. Carney, Emily O. Wirick, Brooke Froelich Murray, and Kristen M. Kwan

Development 2018. 145:None-None; doi: 10.1242/dev.165068