Movie 7

ptch2tc294z mutant trajectories (~12-24 hpf): cells moving to disrupted optic fissure and optic stalk. Trajectories superimposed on average projection of membrane channel (grayscale), with temporal nuclei (blue shades), nasal nuclei (red/yellow shades), and stalk nuclei (purple shades). Time interval between z-stacks, 2.75 minutes. Dorsal view.

Hedgehog signaling regulates cell motility and optic fissure and stalk formation during vertebrate eye morphogenesis

Hannah B. Gordon, Sarah Lusk, Keith R. Carney, Emily O. Wirick, Brooke Froelich Murray, and Kristen M. Kwan

Development 2018. 145:None-None; doi: 10.1242/dev.165068