Movie 1
F-actin dynamics and levels in wild type vs. hum-7(ok3054) embryos. The epidermal-specific transgene, plin-26:: vab-10 ABD::gfp, was used to image the F-actin dynamics in the migrating epidermal cells during embryonic enclosure. Embryos were staged from the 2-cell stage and imaged at 23ÂșC under identical conditions. Ventral is up. In this movie the entire embryos are shown. The center hum-7(ok3054) embryo encloses faster than wild type while the hum-7(ok3054) embryo on the right arrests partway through enclosure. In the right panel the bright signal at the lower left corner is from another embryo.
The RhoGAP HUM-7/Myo9 integrates signals to modulate RHO-1/RhoA during embryonic morphogenesis in Caenorhabditis elegans
Development 2018. 145:None-None; doi: 10.1242/dev.168724