Movie 4

Gastrulation movements of plekhg5 morphant embryos with the MO injected either into the dorsal (left embryo) or the ventral (right embryo) side. The dorsally injected embryo shows defects in blastopore closure. This happens in a minority of the morphant embryos, suggesting a lack of precision in cell movements during gastrulation.

The RhoGEF protein Plekhg5 regulates apical constriction of bottle cells during gastrulation

Ivan K. Popov, Heather J. Ray, Paul Skoglund, Ray Keller, and Chenbei Chang

Development 2018. 145:None-None; doi: 10.1242/dev.168922