Movie 5

Inhibition of p53 mitochondrial pathway with pifithrin-μ does not rescue neural tube closure.
Culture of a 9 somite Ven^Myr mouse embryo with both 15μM TPEN and 50μM pifithrin-μ, an inhibitor of p53 mitochondrial function, does not rescue TPEN-induced failure of neural tube closure (n=5).